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As an alternative, novel strategies are being pursued which allow for rebridging of the reduced disulfide bonds with reagents that carry the cytotoxin

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En relacin a pacientes con insuficiencia cardaca, los GLP1-RA parecen no ser la opcin ms adecuada ya que los inhibidores del SGLT-2 han demostrado de forma consistente la reduccin del riesgo de esta enfermedad y su riesgo de hospitalizacin debido a su efecto diurtico 143

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Environ Sci Technol 50(7):40714081